Hyaluronic acid (HA) is a naturally occurring molecule found in skin, eyes, and joints, where it binds water and supports hydration, elasticity, and smoothness. Levels peak in early adulthood but decline with age, contributing to changes in skin structure and joint comfort.
The essentials
What it is: A glycosaminoglycan, or sugar-based molecule, naturally present in connective tissues and synovial fluid.
Why it matters: HA binds large amounts of water, helping to keep tissues hydrated and cushioned. Declining levels are one of the hallmarks of ageing.
Life stage relevance: HA concentrations decrease from the mid-30s onwards. By midlife, both production and stability are reduced, making replenishment through diet and supplementation a considered strategy for maintaining hydration and comfort.
Food sources
Unlike vitamins and minerals, hyaluronic acid is not found in meaningful amounts in everyday diets. Small traces exist in animal connective tissues such as bone broth, but these are inconsistent and not standardised. For measurable results, supplementation with a defined and bioavailable form, most often sodium hyaluronate, the stable, water-soluble salt of HA, is considered.
Hyabest™ – More than hydration. A benchmark for skin smoothness.
When it comes to hyaluronic acid, not all forms are created equal. Many supplements rely on generic, undefined grades that vary in purity, molecular weight, and bioavailability. Hyabest™ is different: a patented, fermentation-derived sodium hyaluronate developed in Japan with pharmaceutical-grade standards to ensure stability, consistency, and proven absorption.
Behind it stands Kewpie Corporation, a company with more than a century of expertise in biotechnology. As the pioneer of oral hyaluronic acid research, Kewpie has set the global benchmark in purity, safety, and clinical validation. This matters, because only a defined and bioavailable form can deliver results that move beyond promises to measurable transformation.
Clinically proven
In two gold-standard, randomized, double-blind, placebo-controlled human trials, a daily dose of 120 mg Hyabest™ delivered visible improvements within 8–12 weeks:
- Wrinkle reduction (up to –24%)
- Increase in skin hydration (up to +15%)
- Noticeably improved elasticity, suppleness, and overall skin smoothness
These are not surface effects. They are structural changes confirmed by instrumental measurements and participant evaluations, showing that Hyabest™ replenishes where skin needs it most.
Explore The Beauty Complete formula
Hyabest™ sodium hyaluronate is included in our Beauty Complete formula, provided at 120 mg per daily dose (two capsules).
References
Oe, M., Sakai, S., Yoshida, H., Okado, N., Kaneda, H., Masuda, Y., & Urushibata, O. (2017). Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period. Clinical, Cosmetic and Investigational Dermatology, 10, 267-273. https://doi.org/10.2147/CCID.S141845
Hsu, T. F., Chen, Y. C., Yang, Y. H., Lin, C. H., & Lin, Y. J. (2021).
Oral hyaluronan relieves wrinkles and improves dry skin: a 12-week double-blinded, placebo-controlled study. Nutrients, 13(7), 2220. https://doi.org/10.3390/nu13072220
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🇯🇵 Hyabest™ is a trademarked hyaluronic acid, manufactured in Goka, Japan by Kewpie, a pioneer in fermentation-derived hyaluronic acid with decades of expertise. The company is recognised for its pharmaceutical-grade quality, extensive clinical validation, and advanced biotechnological processes that ensure purity, safety, and high bioavailability.
Disclaimer: This article is intended solely for general informational purposes. It does not provide medical advice, diagnosis, or treatment, nor should it be interpreted as making health claims. The content summarises ingredient characteristics based on publicly available research. Individual experiences may differ. For any questions regarding supplementation, nutrition, or personal health, please consult a qualified healthcare professional before making decisions.
