Phytoceramides – Supporting the skin’s natural barrier

Phytoceramides – Supporting the skin’s natural barrier

Phytoceramides in one glance

Ceramides are essential lipids within the skin’s outermost layer, where they lock in moisture and provide a protective shield against daily stressors. As natural ceramide levels decline with age, the barrier weakens, leading to dryness, roughness, and the appearance of fine lines. This decline is a key factor in visible skin ageing, and restoring ceramide balance is central to maintaining skin’s smoothness, elasticity, and comfort.

The essentials

What they are: Plant-derived ceramides, often glucosylceramides, that integrate into the skin barrier and support long-lasting hydration.
Why they matter: A strong ceramide barrier reduces transepidermal water loss (TEWL) and helps preserve elasticity, suppleness, and visible smoothness.
Life stage relevance: From the mid-30s onwards, ceramide production decreases, making supplementation an elegant way to preserve skin vitality.

Natural sources

Phytoceramides occur naturally in grains such as wheat and rice, and in certain vegetables, but levels vary and are not standardised. The amounts needed for visible results are almost impossible to obtain through diet alone. To be effective, phytoceramides must be extracted and processed in a way that preserves their structure and ensures they are bioavailable to the body.

This is also where quality makes a difference. A generic extract may contain ceramides, but without clinical validation against placebo, there is no guarantee of meaningful results. Choosing a unique, standardised extract backed by published human studies is vital if the goal is to achieve real improvements in hydration, elasticity, and visible smoothness.

Three things to look for in a phytoceramide formula

1. Precision and clinical backing – a standardised extract with a clearly defined ceramide profile, supported by human studies demonstrating hydration, elasticity, and barrier improvements.
2. Purity, safety, and traceability – extracts produced under pharmaceutical-grade standards with rigorous testing for stability and safety, and transparent sourcing that confirms plant origin and identity.
3. Intelligent formulation design – phytoceramides thoughtfully combined with synergistic actives such as hyaluronic acid, collagen, or antioxidants for a complete approach to hydration, resilience, and vitality.

Ceramosides™ — our selected phytoceramides

What it is

Ceramosides™ is a gluten-free wheat lipid extract, standardised for phytoceramides (glucosylceramides) and complementary lipids that reinforce the skin barrier. Developed in Europe under strict quality standards, it is designed to deliver results in a small, once-daily dose.

What the research shows

  • Hydration & elasticity: Randomised, placebo-controlled studies show significant improvements within 8–12 weeks.
  • Wrinkle reduction: Clinical imaging demonstrates reduced wrinkle depth and smoother skin compared with placebo.
  • Barrier support: Measurable reductions in TEWL confirm strengthened barrier integrity.

TEWL, or transepidermal water loss, is the evaporation of water through the skin. It is measured with specialised instruments and is considered a gold-standard method in dermatology for assessing skin barrier integrity.

Why we selected it

Ceramosides™ represents a refined, clinically validated form of phytoceramides: standardised, traceable, and effective at low daily doses. Our Beauty complete formula provides 30 mg per daily serving, the level consistently used in published studies—delivering visible improvements in hydration, elasticity, and smoothness.

References

[1] Guillou S, Ghabri S, Jannot C, et al. (2011). Int J Cosmet Sci, 33(2):138–143.
[2] Bizot V, et al. (2017). Cosmetics, 4(4):37.
[3] Seppic (Ceramosides™) clinical dossier: 30 mg/day, 8–12 weeks; moisturisation, elasticity, wrinkles, TEWL.
[4] Sun Q, et al. (2022). Front Nutr, 9:895192.
[5] NutraIngredients report of Ceramosides™ RCT, 56 days vs placebo.

📌 Disclaimer: This article is for informational purposes only and does not offer medical advice or make health claims. It outlines ingredient characteristics based on publicly available research. Individual responses may vary. For personal health decisions, please consult a qualified healthcare professional.